​GC-SOS    Gas Chromatography Simulation & Optimization Software
GC-SOS Gas Chromatography Simulation & Optimization Software. GC-SOS is a Windows app for the simulation and optimization of capillary gas chromatography separations.  It features a rich set of powerful functions in a package designed to be intuitive and easy to use. For GC method development and teaching retention principles. Temperature, Pressure, Flow, Rate, Animation, Automatic Optimization Algorithm, flexible. GC Simulation, retention simulation

​GC-SOS® is an innovative program for the simulation & optimization of Gas Chromatography separations, for method development and teaching of chromatography principles. GC-SOS is the premier simulation tool for developing the most efficient GC methods! 
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Why use GC simulation software?
  • GC method ​development is a time consuming and challenging task. 
  • Even veteran chromatographers find it difficult to manually optimize a method. In fact, it's quite difficult to accurately ​guess how the complex interactions of temperature, pressure and column size impact a separation.
  • Manual trial-and-error approaches often produce sub-optimal separations, ultimately leading to lower performance and higher costs. 
  • Simulation and numerical optimization is the most effective way to achieve significantly faster method development,  improved separation performance and lower analysis costs.

 ​Why use GC-SOS?
  • GC-SOS is the most advanced, powerful, and easy to use GC simulation program available.  First released in 1996, GC-SOS has been used globally by leading companies, universities, and government agencies.  The program was completely upgraded and re-launched in 2017 exclusively online. Our newest version continues a tradition of innovation, with proprietary features including enhanced numerical optimization,  flexible requirements,  improved accuracy,  ​and animation.  
  • A method can be optimized via simulation in just a few minutes.  Simply enter run conditions and retention data from 1 to 3 training run(s), then simulate the effect of new conditions. Instantly evaluate the effect of different temperature &/or pressure programs, or different column sizes.  Use the proprietary Auto-Optimization function to quickly determine an optimal method with improved peak resolution and lower run times in seconds.
  • Optimized methods provide greater separation performance, including improved resolution and lower run costs.
  • Our 100% satisfaction guarantee insures there is no faster, easier, or more effective way to develop the most efficient GC methods.

Watch an 8 minute introductory video:  Youtube Video Introduction

Download a Free Demo​      GC-SOS® software runs on PC's with Microsoft Windows®  7 or later
This separation was optimized in just a few minutes, providing improved resolution and 50% reduction in run-time!

​Example Application

​​Initial separation:
Time = 36 minutes
​Rez(min) = 4.7

​​Optimized separation:
Time = 18 minutes
​Rez(min) = 5.0

net-
improved resolution in 1/2 the time!

​​Simple,  intuitive design

  • Accurate simulations made via a single click- never wait for an experimental run again! 
  • Quickly evaluate the effects of temperature, pressure, or column size changes on your separaton.
  • A high resolution plot shows simulations as they would look on a real instrument. Instant run analysis determines separation efficiency.

A remarkably effective way to optimize separations and demonstrate chromatography principles.
Feedback from GC-SOS users:

" .. well designed and easy to use... an essential tool for method development."

" I like being able to make simulations based on my existing separation."

​" The Automatic-Optimization function is amazing!"

​" .. more effective than traditional trial-and-error approaches."

" Our optimized separations are now significantly more efficient- saving both time and money."

​" We use GC-SOS in our Gas Chromatography training classes."