​GC-SOS Gas Chromatography Simulation & Optimization Software
GC-SOS Gas Chromatography Simulation & Optimization Software. GC-SOS is a Windows app for the simulation and optimization of capillary gas chromatography separations.  It features a rich set of powerful functions in a package designed to be intuitive and easy to use. For GC method development and teaching retention principles. Temperature, Pressure, Flow, Rate, Animation, Automatic Optimization Algorithm, flexible. GC Simulation, retention simulation


GC-SOS has been in use for several years in many leading companies, universities, and government agencies globally, and previously garnered 'Best-Seller' status from our previous distributor.  Originally launched in 1996 and distributed for many years through a series of 3rd party vendors, the program was completely upgraded and re-launched in 2017 exclusively via  www.GC-SOS.com.  The newest version continues a tradition of innovation and adds to a rich list of proprietary innovative features including numerical optimization, flexible input, improved accuracy, and animation.  For more information, download the GC-SOS User's manual here: GC-SOS6 MANUAL.pdf

The 4S Company & Program Author
The 4S Company is a small company offering premier Scientific Software, Services & Support. GC-SOS was developed by Dr. Mark G. Cipollone. The author holds a PhD in Analytical Chemistry from the University of Georgia (USA), and has developed several applications in the areas of chromatography, measurement, color science, and consumer testing. He is an avid chromatographer who actually loves method development and optimization so much, he developed this software!

The GC-SOS Optimization Challenge!
We believe our Automatic-Optimization algorithm is able to predict the most efficient separations possible! If you are able to optimize one of our demo separations better than our Automatic-Optimization algorithm, we'll give you a free GC-SOS software license (value = $399 USD). The success criteria is simple- provide a minimum resolution in the shortest time. Contact us for more details or to submit a challenge result.

100% Satisfaction Guarantee
We offer a 30-day 100% satisfaction guarantee on all purchases. If you are not completely satisfied with your purchase, let us know within 30 days for a full refund.

​​ Feedback from GC-SOS users:

".. well designed and easy to use... an essential tool for method development."

" I like being able to make simulations based on my existing separation."

​"The Automatic-Optimization function is amazing!"

​".. more effective than traditional trial-and-error approaches."

" Our optimized separations are now significantly more efficient- saving both time and money."

​"We use GC-SOS in our Gas Chromatography training classes.""